SLU-PP-332 is a research compound (an estrogen receptor-related orphan receptor (ERR) agonist) that acts as an "exercise mimetic," meaning it replicates many of the cellular and metabolic effects of physical activity.

Potential benefits of SLU-PP-332 include:

Metabolic and Weight Management 

• Mimics exercise effects: It reproduces many of the metabolic and physiological changes associated with aerobic exercise, even in sedentary states.

• Promotes fat loss: Studies indicate it can help reduce white adipose tissue (body fat mass) and increase fat oxidation (burning fat for fuel) without changes to diet or appetite.

• Improves metabolic health: It may improve insulin sensitivity, lower fasting glucose, and enhance glucose tolerance, potentially aiding in the treatment of conditions like obesity, type 2 diabetes, and nonalcoholic fatty liver disease. 

  
  

Muscle Function and Performance

• Enhances endurance: It has been shown to increase running endurance and stamina in mice by boosting mitochondrial function and promoting a shift towards more oxidative, fatigue-resistant muscle fibers.

• Maintains muscle mass: A notable advantage is its potential to maintain muscle mass during weight loss, which is often a challenge with traditional weight loss methods.

• Boosts mitochondrial function: It increases mitochondrial density and efficiency, leading to enhanced energy production (ATP synthesis) within cells. 

  
  

Cardiovascular and Anti-Aging

• Cardioprotective properties: In preclinical models, it has shown potential to improve cardiac contractility and reduce damage in heart failure models.

• Supports healthy aging: By restoring youthful energy metabolism and suppressing age-associated inflammatory markers, it may contribute to longevity and healthy aging.

• Potential organ health support: Early research suggests it may support kidney health and DHEA sulfate production.